aspects of the business. Responsibilities: Analyze high dimension NGS data including both bulk and single-cell RNA-seq and ATAC-seq data from pooled CRISPR screens. Provide input to the computational biology strategy and take responsibility for its day-to-day execution working with cross-functional partners and leadership teams. … snakemake or Nextflow. Basic proficiency with databases is expected. Experience with analysis of bulk and single-cell RNA-seq data and preferably with pooled CRISPR screens, ATAC-seq analysis, DNA methylation age clocks, data from in vitro models, and ageing biology. Experience working in HPC or cloud environments, familiarity with more »
requirements Requirements o BSc degree in life sciences or related discipline o Experience in at least one of the following fields – cell line development, CRISPR, gene editing or iPSC o Ideally first experience in scientific instrument sales for cell biology o Strong data analyses combined with presentation and verbal communication more »
Background/experience in soil microbial strains. Expertise in bacteria engineering, design and construction of genetic systems, and familiarity with the latest techniques (e.g., CRISPR, directed evolution, homologous recombination etc). Ability to present and represent CroBio at international conferences. Nice-to-Have Skills: Proficiency in Python and/or more »
Saffron Walden, Essex, South East, United Kingdom Hybrid / WFH Options
EMBL-EBI
an exciting opportunity to make a significant contribution to development of a new open-source Perturbation Catalogue for harmonised and curated human gene (e.g. CRISPR), variant (e.g. MAVE), and expression (e.g. Perturb-seq) data. This project is funded through the Open Targets consortium, an innovative public-private partnership that uses more »
carry out lab-based cell biology research focused on potential therapeutic targets in cancer. Projects will involve the use of genetic techniques (RNAi/CRISPR), targeted protein degradation, tool compounds and molecular biology to generate key decision-making data in target validation and enable target prioritisation for drug discovery. The more »
with gene editing, cellular therapy and immunology, or in protein production and drug discovery/process development. Experience with gene-editing techniques such as CRISPR/Cas9 is highly desirable. Experience as a FAS or in a customer-facing role is desired but not essential. The company have had great more »
