using: Excel VBA, Detailed knowledge of Fixed Income front to back and/or process mapping skills Experience in financial products, particularly Interest Rate Derivatives Investment Banking is a must Please click here to find out more about our Key Information Documents. Please note that the documents provided contain generic more »
3D cell culture responsible for characterizing both patients derived organoid and patient derived explant model systems. By exploiting patient-derived organoids and explants/derivatives, the Oncology Translational Research team will apply a multimodality analytic approach, plus machine learning models which are coupled with paired patient-derived data feedback, to more »
preclinical development programmes within GSK Oncology TA. The successful candidate will work as part of a team that, by exploiting patient-derived explants/derivatives (PDE), is developing and implementing cutting-edge cellular, genomic and molecular techniques with a multimodality analytic approach, plus machine learning models to improve cancer patient … predict future targeted and/or immuno-therapy susceptibilities. Key Responsibilities Establish cell culture protocols to grow and analyse patient-derived explants (PDE) or derivatives upon reception. Oversight and performing the cell/explant processing and culture. Performing patient-derived explants/derivative quality control steps ( proliferation rate and cytotoxicity … mix of training/expertise in Oncology and Cancer cell biology. Significant experience in cell culture techniques (primary samples/patient-derived explant and derivatives), cytotoxicity analysis. Cellular and molecular Biology skills: cell isolation from human biopsies/samples; culture of normal and tumor cells from primary samples or immortalized more »
preclinical development programmes within GSK Oncology TA. The successful candidate will work as part of a team that, by exploiting patient-derived explants/derivatives, is developing and implementing cutting-edge cellular, genomic and molecular techniques with a multimodality analytic approach, plus machine learning models to improve cancer patient risk … future targeted and/or immuno-therapy susceptibilities. Key Responsibilities Setting up cell protocols for exosomes isolation and characterization from patient-derived explants/derivatives Purify exosomes from the cell culture medium using ultracentrifugation or related method, and related process development and optimization Developing protocols and conducting experiments for analysis more »
