Industrial Placement - Development - Developability and Immunotoxicity Assessment - 9-12 Months
Whittlesford, Cambridgeshire, United Kingdom
Alchemab
assays in-house using primary immune cells and a suite of techniques (cytokine release, Fc receptor binding, and more), enabling us to evaluate antibody safety internally and more efficiently. Data Enrichment via the Datacube Time permitting, you'll also support biomarker analysis by generating new data or mining publicly available data on markers like inflammatory cytokines … and NfL from patient biosamples. This helps us enrich Alchemab's Datacube-our central data repository-making it more powerful for future discovery work. Project Goals You'll contribute to three key areas: EED Team (first 6 months): Produce and purify a small-scale antibody panel, assess in silico risks of each clone, and evaluate and rank them using … high throughput developability assays Translational Team (next 6 months): Set up and optimise immunotoxicity assays in-house, comparing results to external CRO data using control antibodies and a known Alchemab candidate. Datacube Enrichment: Generate or source additional biomarker data (cytokines, NfL) using commercial assays or public databases, supported by our tech team. Techniques & Technologies You'll Use More ❯
Employment Type: Permanent
Salary: GBP Annual
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