to join their growing team on an exciting journey to support the development of advanced therapeutics addressing critical healthcare challenges. You will lead advanced modelling methods, with a focus on generating novel target recommendations, validating them in models, and translating them into therapeutics. Principal Computational Biologist key responsibilities: – Lead … the ‘advanced modelling’ workstreams, and be the point of contact and a role model for advanced modelling within the company. – Maintain strong domain knowledge of leading ‘omic and ‘big data’ computational methods – Drive experimental design & modelling of phenotyping and/or omics data in close collaboration with … together best-in-class Drug Discovery, Drug Development, Product & Project Management capabilities. – Routinely use Python/R for data analyses, in particular data wrangling, modelling and visualisation. – Develop solutions to increase automation, reliability and scalability of our data processing pipelines and workflows. – Lead, co-develop, and run pipelines in more »
optimise processes for the purification of biopharmaceutical products. - Understanding of GMP and QbD considerations in a large scale manufacturing environment. - Understanding and experience with statistical and modelling software and tools. - Understanding of in-process assays such as qPCR, ELISA, HPLC, plate-based spectrometric assays. - Analytical mindset and problem more »
to support the development of advanced RNA medicines for one of the most pressing healthcare challenges of our time. The role will lead advanced modelling methods within a functional genomics and imaging team, with a sharp focus on generating novel target recommendations, validating them in models (including actual human … liver disease. This role will be based at Oxford Science Park. UK remote work is possible, with site visits. Key Responsibilities Lead the ‘advanced modelling’ squad within the In Silico Biology Team, and be the point of contact and a role model for advanced modelling within the company. … Maintain strong domain knowledge of leading ‘omics' and ‘big data’ computational methods Drive experimental design & modelling of deep phenotyping and/or omics data in close collaboration with wet-lab scientists. Work as a member of cross-functional teams bringing together best-in-class Drug Discovery, Drug Development, Product more »
in their ability to create new strategies both independently and with team collaboration A strong background in mathematics and statistics, with good knowledge of statistical models and signal generation Proficiency in back-testing, simulation, and statistical techniques Data-mining skills paired up with data analysis skills. Previous experience more »
role is embedded within the business, partnering with researchers to design and build models in scalable code and implement them into a cutting-edge modelling and analytics infrastructure. The framework will feed the models huge volumes of alternative datasets and in doing so, accurately track and capitalize on the … optimization scenarios. Build production systems for implementing, trading, monitoring, and performance reporting of systematic investment strategies. Implementation of strategies into production level code. Apply statistical and predictive modeling techniques to process and analyze large data sets. Research and attribution of portfolio performance and driving factors. Conduct research and statisticalmore »
to provide comprehensive recommendations in solution design, business process design, business policy setting, and business metric definition Quantitative and analytical skills (financial analysis, mathematical modelling and statistics, etc.) Ability to dive into the data to determine root-cause Desired ability to understand statistical forecasting models Desired ability to more »
