351 to 375 of 7,001 Permanent Python Jobs

A Python Backend Engineer is needed to join growing software house in London who specialise in helping businesses reduce wasteful processes, costs and energy; and improve their ROI. sustainability meets profitability. Our client aims to change how corporate finance works, by replacing static, limited and often stale financial metrics with live data-driven insights sourced from direct connections to their … clients’ systems. You will be joining a strong team of Backend Python Engineers, Data Scientists, and financial experts, who are building the next generation of financial tools. If you're an experience Software Engineer whose passionate about Python, excited by financial technology, and wants to solve complex problems, this could be for you. As a Python Software Engineer, you will … in a supportive, fast-paced startup environment. Requirements: 1st class - 2;1 Degree in Comp Sci or STEM subject from a Top ranked University 3+ years of experience in Python development Tech: Python, FastAPI, Pydantic, PostgreSQL, Numpy, Pandas, AWS DevOps tools: Kubernetes, Docker,Terraform, Jenkins Very strong software engineering principles Enthusiasm for startup environment and cross-functional teams Passion for More ❯

Software Engineer (Python) - BioTech AI Start Up London, 5 days onsite Up to £130k I’m partnering with an AI BioTech start up who are looking for a Backend Engineer to join their lean, high-impact team and help scale their AI systems in real-world healthcare environments. Why this role stands out: Mission-led : Direct impact on improving patient … culture : Work closely with clinicians, scientists, and product teams. Requirements: Degree in Computer Science, Data Science, Engineering, or related field. 3+ years of backend software engineering experience. Proficient in Python and/or JavaScript (Node.js). Experience with CI/CD tools (e.g. GitHub Actions, Azure Pipelines). Familiar with Docker and microservices architecture. Solid understanding of RESTful APIs. Bonus … Experience with AI/ML tools like Hugging Face, LangChain, or PyTorch. Tech Stack: Python/JavaScript (Node.js) Docker/Kubernetes Azure/GitHub Actions RESTful APIs/Microservices Hugging Face, LangChain, PyTorch Unfortunately, no sponsorship is available at this time. More ❯

Software Engineer (Python) - BioTech AI Start Up London, 5 days onsite Up to £130k I’m partnering with an AI BioTech start up who are looking for a Backend Engineer to join their lean, high-impact team and help scale their AI systems in real-world healthcare environments. Why this role stands out: Mission-led : Direct impact on improving patient … culture : Work closely with clinicians, scientists, and product teams. Requirements: Degree in Computer Science, Data Science, Engineering, or related field. 3+ years of backend software engineering experience. Proficient in Python and/or JavaScript (Node.js). Experience with CI/CD tools (e.g. GitHub Actions, Azure Pipelines). Familiar with Docker and microservices architecture. Solid understanding of RESTful APIs. Bonus … Experience with AI/ML tools like Hugging Face, LangChain, or PyTorch. Tech Stack: Python/JavaScript (Node.js) Docker/Kubernetes Azure/GitHub Actions RESTful APIs/Microservices Hugging Face, LangChain, PyTorch Unfortunately, no sponsorship is available at this time. More ❯

Python Software Engineer – Security & AI Projects Gloucester – Hybrid (2–3 days on-site) Up to £70,000 + Excellent Benefits **Must be a British Citizen** Join one of the UK’s leading technology and defence engineering consultancies — a team trusted by government and security clients to deliver advanced data, software, and AI-driven solutions that protect the country’s most … critical systems. They’re expanding their Gloucester engineering function by 30+ people before Q1 next year, with opportunities for experienced Python Engineers to work on projects that genuinely make a difference. What you’ll be doing Building secure, high-performance software underpinning security and defence operations Developing complex data pipelines, APIs, and AI tooling in modern Python environments Working in … agile, multi-disciplinary teams alongside experts in software, data, and machine learning Delivering production-grade solutions across cloud and on-prem secure environments Experience required Strong hands-on Python development (FastAPI, Flask, Django or similar) Solid understanding of CI/CD pipelines, automated testing, and modern DevOps practices Experience in secure systems, data engineering, or AI-focused environments UK Citizen More ❯

and AI-powered services, with an emphasis on trust, resilience, and common digital standards. Candidates will join a cross-functional team shaping next-generation public services through cutting-edge Python engineering and AI. Overview The Python Developer will design and implement high-performance, secure services in the Business Layer, enabling personalised, AI-driven citizen services. Responsibilities Develop and maintain APIs … and services using Python, FastAPI/Django/Flask, and modern cloud tooling. Build secure and performant integrations between the Business Layer and other systems. Design and optimise data pipelines and transformation logic for large-scale services. Contribute to highly available, fault-tolerant workloads supporting millions of daily interactions. Collaborate within agile teams alongside product owners, architects, and engineers. Essential … Skills Proven Python development experience in production. Strong knowledge of RESTful APIs and asynchronous frameworks (FastAPI, AsyncIO, etc.). Experience with cloud environments (AWS – Lambda, API Gateway, Serverless). Solid understanding of SQL/NoSQL databases and caching technologies (Redis, DynamoDB, PostgreSQL). Active UK Security Clearance. Desirable Experience building or securing mission-critical, public-facing systems. Background in AI More ❯

Great opportunity for Senior Python Engineers to work remotely for a UK based AI scale-up. You'd join a large engineering department and would work within a cross functional product-based team responsible for building cloud-native, event-driven systems in a collaborative DevOps environment. The teams are responsible for all aspects of the product they work on, from … supporting systems in production, so you should expect to apply XP techniques like TDD and SOLID and be comfortable with practices like IaC, CI/CD and Observability. Skills: Python GCP, AWS Kubernetes, Docker, ECS FastAPI, Django PostgreSQL, MongoDB Serverless, Container-based and Event Driven Architectures The money is good too – up to £100k plus benefits including bonus, share options More ❯

Senior Python/AI Engineer Compustaff is partnering with a leading global asset manager to hire a Senior Python/AI Engineer for its Fixed Income Credit team. You’ll build production-grade AI applications and robust Python services that turn unstructured financial data into real insight for analysts and portfolio managers. The role is based in Donegal, with … days required at the office. Why this role Real impact: Ship AI features that directly influence credit research and investment decisions. Modern stack: AWS Bedrock, Python/FastAPI, RAG/GraphRAG, vector databases, and strong automated testing. Engineering culture: Clean code, measurable quality, and shipping to production—regularly. What you’ll do Design and deliver advanced AI applications on AWS … Bedrock (including Converse API interfaces). Build high-performance Python/FastAPI services with comprehensive automated tests. Implement RAG/GraphRAG architectures using knowledge graphs and vector DBs (e.g., OpenSearch , Neptune Analytics ). Create scalable API endpoints for model serving; optimize latency, throughput, and cost . Develop evaluation frameworks and load testing (e.g., Locust ) to ensure reliability at scale. Establish More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

2x Python Developers – NHS OR Central Gov. experience is ESSENTIAL *Full Stack; Python, Vue and AWS* Location: Leeds 1-2x per Month Contract Type: Contract Rate: £500/day Inside IR35 Duration : Until December 2026 (13 Months) Overview We’re working with a digital consultancy delivering modern, user-centred technology solutions within the NHS. They’re looking for an … experienced Python Developer who can help build and maintain scalable applications that directly improve public services. You’ll join a multidisciplinary team working in an Agile environment collaborating with designers, engineers, and data specialists to create impactful products used by thousands nationwide. Key Responsibilities Develop, test, and maintain Python-based APIs and back-end services . Work closely with front … solutions. Write clean, maintainable, and well-documented code following GDS and NHS digital standards. Participate in sprint planning, code reviews, and continuous improvement initiatives. Essential Skills Strong experience with Python (Django, Flask, or FastAPI). Experience building Vue.js front-ends or similar JavaScript frameworks. Proficiency with AWS (Lambda, S3, ECS, CloudFormation, etc.). Familiarity with CI/CD pipelines and More ❯

Senior Python Engineer | Fully Remote | High-Growth Startup (AI/Data/Cloud) Join one of the most exciting early-stage startups of the year — backed by previous huge success, led by an exceptional founding team, and already showing incredible product-market fit. This is a rare opportunity to get in early, take real ownership, and build the foundations of … platform at scale. You’ll work with cutting-edge technology, solve complex challenges, and see your work have a direct impact every single day. The Role As a Senior Python Engineer , you’ll be a key part of a small, high-performing team building scalable backend systems and data-driven products. You’ll shape architecture decisions, drive engineering best practices … and collaborate across teams to deliver impactful features at speed. What You’ll Be Doing Designing and building reliable, high-performance services in Python (FastAPI, Flask, or Django) Leading architecture discussions and mentoring junior engineers Collaborating with product, data, and design teams to bring ideas to life Building scalable systems in the cloud (AWS/GCP/Azure) Driving quality More ❯

Opportunity & Requirement Summary 📛 Role | Python Software Engineer 🔵 Company | Growing SaaS Software Provider 📏 Size | 15–20 employees 📍 Location | London (Hybrid – 3 days per week in the office) 💰 Offer | £60,000 – £90,000 + share options + benefits Detailed Overview Kioni Talent is partnering with an innovative SaaS company that’s helping businesses streamline complex workflows through their intelligent software platform. They … re now looking for a Python Software Engineer to join their close-knit team and play a key role in building and scaling the backend that powers their core product. You’ll be joining a collaborative engineering team of experienced developers, product thinkers, and problem-solvers — all passionate about writing clean, scalable code and continuously improving their platform. ⭐ What You … ll Do Design, build, and maintain backend services using Python (Django/FastAPI) Contribute to architecture and technical design discussions Write clean, maintainable, and well-tested code Work closely with Product and Frontend teams to deliver new features Help improve scalability, performance, and reliability as the platform grows 💥 Your Impact Be a key contributor in a product-led SaaS company More ❯

Python Engineer £750 - £800 per day 2 days onsite We're working with a global healthcare and AI research organisation that's pioneering the use of advanced Machine Learning to accelerate the discovery and delivery of life-changing treatments. Their vision is to enable faster, personalised therapies that improve patient outcomes worldwide - and they're seeking a Backend Software Engineer … joining a multidisciplinary AI/ML team responsible for developing the infrastructure and software that powers cutting-edge research and intelligent applications. The role focuses on backend development in Python, integrating AI components with data, compute, and frontend systems to create scalable, high-performance solutions. Day-to-day responsibilities include: Designing and implementing backend services for Python-based web applications … engineers, and ML specialists to build end-to-end pipelines. Participating in agile ceremonies and code reviews to uphold quality and delivery standards. Tech Stack & Skills Core skills: Strong Python backend development experience (FastAPI or similar frameworks) Cloud-native deployment experience (preferably Google Cloud and Cloud Run) Unit testing experience (pytest or similar frameworks) Familiarity with agile development and CI More ❯

Great opportunity for Senior Python Engineers to work remotely for a UK based AI scale-up. You'd join a large engineering department and would work within a cross functional product-based team responsible for building cloud-native, event-driven systems in a collaborative DevOps environment. The teams are responsible for all aspects of the product they work on, from … supporting systems in production, so you should expect to apply XP techniques like TDD and SOLID and be comfortable with practices like IaC, CI/CD and Observability. Skills: Python GCP, AWS Kubernetes, Docker, ECS FastAPI, Django PostgreSQL, MongoDB Serverless, Container-based and Event Driven Architectures The money is good too – up to £100k plus benefits including nonus, share options More ❯

in AI-driven automation software. You’ll join a team dedicated to pushing the boundaries of what’s possible in the trading world, using innovation to drive real results. Python AI/API Engineer – London What you will do Maintain and develop the AI offering, pioneering innovative approaches to achieve the company's vision. For example, integrating cutting-edge AI … and participating in code reviews. Keep abreast of new & developing technologies - championing/incorporating when appropriate. What you’ll need to succeed Minimum of 3+ years of experience with Python and major cloud providers (AWS, Azure, or GCP). Proven experience in building Rest APIs with frameworks such as Flask/FastAPI. Strong Experience in software development best practices: CI More ❯

in AI-driven automation software. You’ll join a team dedicated to pushing the boundaries of what’s possible in the trading world, using innovation to drive real results. Python AI/API Engineer – London What you will do Maintain and develop the AI offering, pioneering innovative approaches to achieve the company's vision. For example, integrating cutting-edge AI … and participating in code reviews. Keep abreast of new & developing technologies - championing/incorporating when appropriate. What you’ll need to succeed Minimum of 3+ years of experience with Python and major cloud providers (AWS, Azure, or GCP). Proven experience in building Rest APIs with frameworks such as Flask/FastAPI. Strong Experience in software development best practices: CI More ❯