Principal Data Scientist Jobs in England

26 to 39 of 39 Principal Data Scientist Jobs in England

Senior/Principal Data Scientist - Single Cell

London, United Kingdom
Relation Therapeutics Limited
Senior/Principal Data Scientist - Single Cell London About Relation Relation is an end-to-end biotech company developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life's most devastating diseases. We leverage single-cell multi-omics directly from patient tissue … to advance the field of drug discovery. Your work will shape our culture, strategic direction, and, most importantly, impact patients' lives. Opportunity This is a unique opportunity for a data scientist to work on multi-omics and perturbational data to drive transformative insights into drug discovery. As a member of the Single Cell and Spatial Omics team … and embedded within one of the ML research teams, you will contribute advanced data analysis and domain expertise to challenge ML models that aim to predict and explain cellular decision-making in disease. Your responsibilities Develop and implement computational workflows for integrating and analysing multi-omics data. Design statistical models for analysing transcriptomics and other omics datasets. Use domain More ❯
Employment Type: Permanent
Salary: GBP Annual
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Principal Data Scientist (London)

London, UK
Microsoft
person and every organization on the planet to achieve more. Microsoft believes that artificial intelligence will play a critical role in accomplishing that mission. We're looking for a Principal Data Scientist to help shape the future of Microsoft 365 Copilot, with a focus on Search, Chat and Research experiences.This role sits within the Microsoft Search, Assistant … and Intelligence (MSAI) organization, which powers the intelligence behind M365 Copilot by combining cutting-edge advances in generative AI with personalized search and recommendation systems. As a Principal Scientist in MSAI, you will work in an exciting and fast-paced, collaborative environment. You'll bring deep expertise in large language models (LLMs), information retrieval, and machine learning to … reasoning in Microsoft 365 Copilot by applying next-generation LLM fine-tuning and reinforcement learning techniques. Improving Copilot Chat and Researcher response quality through state-of-the-art grounding data selection strategies. Enhancing Copilot Search by developing novel content representation models. Building the next wave of recommendation and personalization capabilities across M365 Copilot experiences. In addition to driving innovation More ❯
Employment Type: Full-time
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Principal Data Scientist

London Area, United Kingdom
Harnham
Principal Data Scientist Up to £150,000 London (Hybrid, 2-3 days onsite per week) Company: This private equity and investment start-up are focused on streamlining and improving performance by reimagining value creation capabilities. They are utilising cutting-edge AI to generate performance insights on each aspect of the investment lifecycle. Responsibilities: Build machine learning predictive … a fast-paced, collaborative environment. How to Apply: Please register your interest by sending your CV to Emily Burgess via the Apply link on this page. Keywords: Machine Learning, Data Science, start-up, Investment, Equity More ❯
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Principal Data Scientist

City of London, London, United Kingdom
Harnham
Principal Data Scientist Up to £150,000 London (Hybrid, 2-3 days onsite per week) Company: This private equity and investment start-up are focused on streamlining and improving performance by reimagining value creation capabilities. They are utilising cutting-edge AI to generate performance insights on each aspect of the investment lifecycle. Responsibilities: Build machine learning predictive … a fast-paced, collaborative environment. How to Apply: Please register your interest by sending your CV to Emily Burgess via the Apply link on this page. Keywords: Machine Learning, Data Science, start-up, Investment, Equity More ❯
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Principal Data Scientist

London Area, United Kingdom
Harnham
Lead/Principal Data Scientist London – Hybrid (3 days a week) £90,000 - £115,000 + Benefits Our client is a precision marketing agency, leveraging data, technology, and creativity to fuel client growth. As part of their Marketing Sciences Data Science Team, you’ll play a pivotal role in revolutionising marketing strategies through cutting-edge … Data Science and Machine Learning solutions. This is still a largely hands on role, with around 20% team leadership. What You’ll Do Oversee data science projects, guide junior team members, and drive innovation. Build predictive models for campaign optimisation, customer segmentation, and price elasticity. Design and implement AI-powered solutions to solve complex marketing challenges. Use machine … in tools like Jupyter notebooks, Pandas, and PyTorch. Expertise in cloud platforms (AWS, Databricks, Snowflake) and containerisation tools (Docker, Kubernetes). Strong leadership skills with experience mentoring and managing data science teams. Deep knowledge of media measurement techniques, such as media mix modelling. Experience with advanced AI techniques, including NLP, GenAI, and CausalAI. Familiarity with MLFlow, API design (FastAPI More ❯
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Principal Data Scientist

City of London, London, United Kingdom
Harnham
Lead/Principal Data Scientist London – Hybrid (3 days a week) £90,000 - £115,000 + Benefits Our client is a precision marketing agency, leveraging data, technology, and creativity to fuel client growth. As part of their Marketing Sciences Data Science Team, you’ll play a pivotal role in revolutionising marketing strategies through cutting-edge … Data Science and Machine Learning solutions. This is still a largely hands on role, with around 20% team leadership. What You’ll Do Oversee data science projects, guide junior team members, and drive innovation. Build predictive models for campaign optimisation, customer segmentation, and price elasticity. Design and implement AI-powered solutions to solve complex marketing challenges. Use machine … in tools like Jupyter notebooks, Pandas, and PyTorch. Expertise in cloud platforms (AWS, Databricks, Snowflake) and containerisation tools (Docker, Kubernetes). Strong leadership skills with experience mentoring and managing data science teams. Deep knowledge of media measurement techniques, such as media mix modelling. Experience with advanced AI techniques, including NLP, GenAI, and CausalAI. Familiarity with MLFlow, API design (FastAPI More ❯
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Principal Data Scientist (London)

London, UK
ZipRecruiter
Job Description Lead/Principal Data Scientist London Hybrid (3 days a week) 90,000 - 115,000 + Benefits Our client is a precision marketing agency, leveraging data, technology, and creativity to fuel client growth. As part of their Marketing Sciences Data Science Team, youll play a pivotal role in revolutionising marketing strategies through cutting … edge Data Science and Machine Learning solutions. This is still a largely hands-on role, with around 20% team leadership. What Youll Do Oversee data science projects, guide junior team members, and drive innovation. Build predictive models for campaign optimisation, customer segmentation, and price elasticity. Design and implement AI-powered solutions to solve complex marketing challenges. Use machine … in tools like Jupyter notebooks, Pandas, and PyTorch. Expertise in cloud platforms (AWS, Databricks, Snowflake) and containerisation tools (Docker, Kubernetes). Strong leadership skills with experience mentoring and managing data science teams. Deep knowledge of media measurement techniques, such as media mix modelling. Experience with advanced AI techniques, including NLP, GenAI, and CausalAI. Familiarity with MLFlow, API design (FastAPI More ❯
Employment Type: Full-time
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Principal Data Scientist - AI (London)

London, UK
Hybrid / WFH Options
Opus 2
We're looking for a Principal Data Scientist to lead the design of AI systems that can support complex, multi-step tasks, use tools, adapt to context, and make intelligent decisions. You'll work closely with product and engineering to architect LLM-powered features that are robust, useful, and production-ready not just impressive demos. This role … is ideal for someone who not only understands data and AI deeply but also brings strong software engineering instincts. Someone who can design intelligent systems that operate reliably and scalably within a complex product environment. What you'll be doing You will explore and implement RAG or Graph RAG approaches to improve retrieval quality and reasoning in LLM workflows … helping shape how we scale LLM usage responsibly across the platform. You bridge product and engineering by embedding AI into user-facing features, not just prototypes. Collaborate closely with Principal Engineer to align AI workflows, system prompts, and model interaction layers. What excites us? We've moved past experimentation. We have live AI features and a strong pipeline of More ❯
Employment Type: Full-time
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Principal Data Scientist (London)

Hanwell, Greater London, UK
Temenos
the power to create their own destiny and make a positive contribution to the world of banking and society. THE ROLE We are seeking a visionary and hands-on Principal Data Scientist to lead the design, development, and deployment of cutting-edge AI/ML solutions across our Banking AI portfolio. This role is central to Temenos … operate and serve their customers. You will work closely with product managers, engineers, and domain experts to build scalable, ethical, and high-performing AI systems. You will also mentor data scientists, contribute to AI governance, and drive innovation in areas such as GenAI, LLMs, and predictive analytics. OPPORTUNITIES AI Strategy & Innovation Lead research and prototyping of novel AI techniques … models into scalable, cloud-native and on-prem systems. Establish best practices for model monitoring, retraining, and lifecycle management. Technical Leadership & Mentorship Provide technical direction and mentorship to junior data scientists and engineers. Review code, model architectures, and experiments to ensure scientific rigor and quality. Contribute to the development of internal AI frameworks, tools, and reusable components. Stakeholder Engagement More ❯
Employment Type: Full-time
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Principal, AI Data Scientist-1 (Remote) (London)

London, UK
Hybrid / WFH Options
Jazz Pharmaceuticals
The Principal, AI Data Scientist will be responsible for supporting the implementation of innovative, complex and transformative AI/ML/GenAI solutions across the areas of Clinical Trial Execution and Digital Healthcare across Jazz Research and Development. Essential Functions Support the development and implementation of AI/ML/GenAI solutions to optimize clinical trial operations … including such areas as patient recruitment, patient retention, real-time data monitoring and automated data collection system build. Support the development and implementation GenAI applications for automated clinical trial documentation generation including such areas medical reports, clinical study reports, protocols and patient narratives. Support the development and implementation of Digital Healthcare applications for medical and scientific tools, RWE … new ways of generating real data, patients engagement. Support the esign and develop predictive models and generative AI solutions using diverse healthcare data sources, including clinical trials data, electronic health records, wearable devices, patient-reported outcomes, HEOR data, phase IV studies. Collaborate with cross-functional teams including clinical operations, clinical development, data science and global More ❯
Employment Type: Full-time
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Principal Data Scientist (London)

Wandsworth, Greater London, UK
LinuxRecruit
constant curiosity, and a willingness to challenge how things have always been done. Thats exactly the mindset this rapidly expanding European tech company is looking for in its next Principal Data Scientist. As they continue to scale off the back of real success, their mission is clear: make AI more accessible and impactful for businesses everywhere. Their intelligent … products help organisations tap into the power of data to drive smarter decisions, uncover hidden opportunities, and transform operations, and youll play a key role in making that happen. In this role, youll be responsible for leading a talented team of data scientists and ML engineers, helping to architect, build, and refine intelligent systems from the ground up. … and experimentation to production deployment and performance monitoring. Setting high standards while creating space to learn and grow through trial and iteration. Youll bring a deep understanding of modern data science and machine learning techniques and know when to apply the right tools, whether thats deep learning, statistical modelling, or classical ML methods. Your toolkit includes Python, SQL, and More ❯
Employment Type: Full-time
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Principal Data Scientist - Microsoft 365 Copilot

London, United Kingdom
Microsoft
reasoning in Microsoft 365 Copilot by applying next-generation LLM fine-tuning and reinforcement learning techniques. - Improving Copilot Chat and Researcher response quality through state-of-the-art grounding data selection strategies. - Enhancing Copilot Search by developing novel content representation models. - Building the next wave of recommendation and personalization capabilities across M365 Copilot experiences. - In addition to driving innovation … in deploying machine learning applications at scale in real production environments and proven track record of successfully shipping applied research to production is a must - Excellent problem solving and data analysis skills and a good grasp of applied statistics. Particularly, expertise in developing or applying predictive analytics, statistical modelling, data mining, or machine learning algorithms, especially at scale More ❯
Employment Type: Permanent
Salary: GBP Annual
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Principal Data Scientist - Opportunity in Sydney, Australia (London)

London, UK
Commonwealth Bank of Australia
building robust Generative AI and Machine Learning capabilities that shape the future of customer engagement, business intelligence, and innovation. You will technically drive your team to deliver world-class data science and AI capabilities across RBS and the Group. Our strategic focus is on positioning the Group at the forefront of AI innovation, delighting our customers at every interaction … AI. What You'll Do: Set and communicate a clear AI vision aligned with business goals. Lead the development of innovative solutions to complex challenges using advanced AI and data science. Stay ahead of industry trends by applying new technologies and research. Provide strategic and technical leadership across AI projects, ensuring excellence in delivery. Collaborate with top AI and … data science talent to build a high-performance culture. Partner with internal teams and external experts to share knowledge and drive AI-led impact. Expand the use of Generative and Agentic AI to improve customer experiences and simplify operations. Upskill teams in Gen AI techniques like prompt design, RAG, fine-tuning, and agentic frameworks. Build reusable Gen AI frameworks More ❯
Employment Type: Full-time
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Principal Data Scientist

London, United Kingdom
Temenos Headquarters SA
has the power to create their own destiny andmake a positive contribution to the world of banking and society. THE ROLE We are seeking a visionary and hands-onPrincipal Data Scientistto lead the design, development, and deployment of cutting-edgeAI/ML solutionsacross our Banking AI portfolio. This role is central to Temenos' AI strategy, delivering responsible, high-impact … operate and serve their customers. You will work closely with product managers, engineers, and domain experts to build scalable, ethical, and high-performing AI systems. You will also mentor data scientists, contribute to AI governance, and drive innovation in areas such as GenAI, LLMs, and predictive analytics. OPPORTUNITIES AI Strategy & Innovation Lead research and prototyping of novel AI techniques … models into scalable, cloud-native and on-prem systems. Establish best practices for model monitoring, retraining, and lifecycle management. Technical Leadership & Mentorship Provide technical direction and mentorship to junior data scientists and engineers. Review code, model architectures, and experiments to ensure scientific rigor and quality. Contribute to the development of internal AI frameworks, tools, and reusable components. Stakeholder Engagement More ❯
Employment Type: Permanent
Salary: GBP Annual
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